DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy
Feb 23, 2017Author：
Title: DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy Authors: Du, Y; Jiang, Q; Beziere, N; Song, LL; Zhang, Q; Peng, D; Chi, CW; Yang, X; Guo, HB; Diot, G; Ntziachristos, V; Ding, BQ; Tian, J Author Full Names: Du, Yang; Jiang, Qiao; Beziere, Nicolas; Song, Linlin; Zhang, Qian; Peng, Dong; Chi, Chongwei; Yang, Xin; Guo, Hongbo; Diot, Gael; Ntziachristos, Vasilis; Ding, Baoquan; Tian, Jie Source: ADVANCED MATERIALS, 28 ( 45):10000-10007 ; 10.1002/adma.201601710 DEC 7 2016 Language: English Abstract: A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo. ISSN: 0935-9648 eISSN: 1521-4095 IDS Number: EI8AA Unique ID: WOS:000392725200011 PubMed ID: 27679425